C8 having two peptide chains: C8β and C8αϒ. Binding of C8β with C5b67 complex causes conformational change in the C8 dimer such that hydrophobic domain of C8αϒ can insert into the interior of the phospholipid membrane.

TLS Online TPP Program

#Id: 1858

#Unit 3. Fundamental Processes

TATA less, Inr Less promoters uses Sp1 activator to position TBP with TAFs

TLS Online TPP Program

#Id: 1859

#Unit 3. Fundamental Processes

Sp1 (Mr  80,000) is a transcription activator for a large number of genes in higher eukaryotes. Its DNA binding site, the GC box consensus sequence GGGCGG.

TLS Online TPP Program

#Id: 1860

#Unit 3. Fundamental Processes

Sp1 contains three zinc fingers, 25% of their amino acid residues are Gln.

TLS Online TPP Program

#Id: 1861

#Unit 3. Fundamental Processes

RNA polymerase III transcribes a set of short genes. The classical class III genes (types I and II) have promoters that lie wholly within the genes.

 

TLS Online TPP Program

#Id: 1862

#Unit 3. Fundamental Processes

RNA Polymerase I has a Bipartite Promoter

 

TLS Online TPP Program

#Id: 1981

#Unit 3. Fundamental Processes

This structure is called a cap.