TLS Online TPP Program

#Id: 8867

#Unit 2. Cellular Organization

Cdc25B is act as a starter phosphatase that initiates CDK1 activation

Cdc25C is the workhorse phosphatase that activates the vast majority of cyclin-CDK1 complexes

TLS Online TPP Program

#Id: 6502

#Unit 3. Fundamental Processes

Sites of phosphorylation on the CTD serve as a recognition or anchor point for other proteins to dock with the polymerase. The capping enzyme (guanylyl transferase), which adds the G residue to the 5' end of newly synthesized mRNA, binds to CTD phosphorylated at serine 5, the first phosphorylation event catalyzed by TFIIH. 

P-TEFb leads to recruitment of a set of proteins called SCAFs to the CTD, and they in turn bind to splicing factors. This may be a means of coordinating transcription and splicing.

TLS Online TPP Program

#Id: 10317

#Unit 4. Cell Communication and Cell Signaling

Cytotoxic T Cells target tumor cells

Most tumor cells, express MHC class I molecules on their surface, cytotoxic T cells can directly recognize them. 

cytotoxic T cells can result in killing of the tumor cells by two different mechanisms

TLS Online TPP Program

#Id: 175

#Unit 5. Developmental Biology

In instructive interaction, 

a signal from the inducing cell is necessary for initiating new gene expression in the responding cell.

TLS Online TPP Program

#Id: 3860

#Unit 5. Developmental Biology

The phosphoryl group is transferred,

From histidine residue of DhkC  aspartate of DhkC histidine in phospho-transfer intermediate RdeA aspartate of RR of RegA