Following statements are regarding to protein kinase A which phosphorylates multiple intracellular target proteins expressed in different cell types.

A. Inactive PKA is a tetramer consisting of two regulatory (R) subunits and two catalytic (C) subunits.

B. Each R subunit contains a pseudo-substrate domain whose sequence resembles that of a peptide substrate and binds to the active site in the catalytic domain but is not phosphorylated; thus the pseudo-substrate domain inhibits the activity of the catalytic subunits.

C. active PKA is turned off by binding of cAMP Each R subunit has two distinct cAMP-binding sites, called CNB-A and CNB-B.

D. Binding of cAMP by an R subunit of PKA occurs in a cooperative fashion; that is, binding of the first cAMP molecule to CNB-B increases the Kd for binding of the second cAMP to CNB-A. Thus small changes in the level of cytosolic cAMP can cause proportionately large changes in the number of dissociated C subunits and, hence, in cellular kinase activity.

Which of the following statements are incorrect?

#Question id: 3515

#Unit 8. Inheritance Biology

What proportional of F2 round seeded plant would produce all round plant after self fertilization?

#Question id: 3516

#Unit 8. Inheritance Biology

Cross allowed between pure line tall plant with pure line dwarf plant , all F1 having tall phenotype were allowed to self to produced  200 plant The number of F2 plant having pure line tall phenotype?

#Question id: 3517

#Unit 8. Inheritance Biology

The following two genotypes are crossed: AaBbCcddX AabbCcDd. What will number of different genotypes among the progeny of this cross?

#Question id: 3518

#Unit 8. Inheritance Biology

Assume that the trihybrid cross AA BB rr X aa bb RR is made in a plant species in which A and B are dominant but there is incomplete dominance between R and r. Consider the F2 progeny from this cross, and assume independent assortment. The phenotypes appear in this F2 progeny?

#Question id: 3519

#Unit 8. Inheritance Biology

If quadruple heterozygote of genotype Aa Bb Cc Dd is self-fertilized, what is the probability of a quadruple heterozygote Aa Bb Cc Dd offspring is assuming independent assortment of all four pairs of alleles.

#Question id: 3520

#Unit 8. Inheritance Biology

flower colour  in plant  RR- red , rr- white , Rr- pink  and height of plant ( TT,Tt-tall)  ,(tt- dwarf), If cross allowed between plant RrTt X Rrtt, then what probability of progeny plant having pink flower and dwarf variety ?