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TLS Online TPP Program

#Question id: 14766

Which of the following statements does not belongs to the regulatory mechanism of the Arp2/3 complex by WASp and PI(4,5)P2?

#Unit 2. Cellular Organization
  1. The NPF WASp is inactive due to an intramolecular interaction that masks the WCA domain. 
  2. NPF WASp is activated by a coincidence detection mechanism, it must bind both the regulatory phospholipid PI(4,5)P2 though its basic domain (B) and the membrane-bound active small G protein Cdc42-GTP through its Rho-binding domain. 
  3. When activated by the Cdc42-GTP, the intramolecular interaction in WASp is relieved, allowing the W domain to bind actin and the acidic A domain to activate the Arp2/3 complex.
  4. The Arp2/3 branch makes a characteristic 70° angle between the old and new filaments.
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TLS Online TPP Program

#Question id: 3843

#Unit 3. Fundamental Processes

In DNA replication in E. coli, the enzyme primase is used to attach a 5 to 10 base ribonucleotide strand complementary to the parental DNA strand. The RNA strand serves as a starting point for the DNA polymerase that replicates the DNA. If a mutation occurred in the primase gene, which of the following results would you expect?
TLS Online TPP Program

#Question id: 6572

#General Aptitude

Which term comes next in the sequence : Z, U, Q, ?, L
TLS Online TPP Program

#Question id: 3651

#Unit 3. Fundamental Processes

__________________is spontaneous hydrolytic reaction that involves cleavage of the N-glycosylic bond between N-9 of the purine bases A and G and C-1 of the deoxyribose sugar and hence loss of purine bases from the DNA.
TLS Online TPP Program

#Question id: 2192

#Unit 2. Cellular Organization

Site-directed cross-linking is a technique that gives insight into what property of integral membrane proteins?
TLS Online TPP Program

#Question id: 33519

#Unit 2. Cellular Organization

Assertion: Some genes are present in more than one copy or are related to one another. 
Reason: Number of different types of genes is less than the total number of genes.