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TLS Online TPP Program

#Question id: 16139

 Many mouse genes are “tissue-specific,” that is, they are present throughout the body but are expressed in only one of the animal’s many tissue types. (Other mouse genes are expressed throughout the body, or in multiple tissues.) Geneticists can study the regulation of a mouse gene by fusing the gene’s promoter region to the LacZ coding sequence and injecting the construct to create a transgenic mouse. Fusion of the mouse amylase promoter to LacZ yielded a Pamylase-LacZ construct.              
Mice heterozygous for the resulting Pamylase-LacZ  transgene displayed the LacZ expression exclusively in the pancreas. Would you expect homozygotes for the transgene to also display LacZ expression in the pancreas?.

#Unit 13. Methods in Biology
  1. Mice homozygous for the transgene to display LacZ expression in the pancreas differ  from  the heterozygous mouse does, homozygote is a result of a cross between two heterozygous mice of the opposite transgenic line.
  2. Mice homozygous for the transgene to display LacZ expression in the pancreas is unlikely to the heterozygous mouse does, homozygote is a result of a cross between two homozygous mice of the same transgenic line.
  3. Mice homozygous for the transgene to display LacZ expression in the pancreas as the heterozygous mouse does, homozygote is a result of a cross between two homozygous mice of the different  transgenic line.
  4. Mice homozygous for the transgene to display LacZ expression in the pancreas as the heterozygous mouse does, homozygote is a result of a cross between two heterozygous mice of the same transgenic line.
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TLS Online TPP Program

#Question id: 15446

#Unit 4. Cell Communication and Cell Signaling

Hyper IgM syndrome caused by mutation in?
TLS Online TPP Program

#Question id: 15447

#Unit 4. Cell Communication and Cell Signaling

During development two types of B-cells will be formed:- 
I) T1 cell
II) T2 cell
Some features about T1 and T2 cells given in below;
a) Maturity achieve
b) Found in blood circulation
c) Presence of  Immunoglobulin IgM high and IgD low
d) Expressing CD21 and CD23
e) Cell expressing BAFF-R, Which bind with BAFF survival factor
Match the cell with their correct features;
TLS Online TPP Program

#Question id: 15448

#Unit 4. Cell Communication and Cell Signaling

Stimulation of a single B cell would result in the generation of a clone of cells having_____
TLS Online TPP Program

#Question id: 15449

#Unit 4. Cell Communication and Cell Signaling

Class switch recombination of B-cell that is generated upon recognition of protein antigens and requires the participation of_____
TLS Online TPP Program

#Question id: 15450

#Unit 4. Cell Communication and Cell Signaling

T-cell dependent response requires a signal is provided by an activated T cell, which binds to the B cell through,
a) lipopolysaccharide moiety
b) its antigen receptor 
c) A separate interaction between CD40L on the B cell and CD40 (CD154) on the activated TH cell
d) A separate interaction between CD40 on the B cell and CD40L (CD154) on the activated TH cell
TLS Online TPP Program

#Question id: 15451

#Unit 4. Cell Communication and Cell Signaling

T-cell dependent, B-cell activation require many signals except___