Practice Questions

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#Question id: 16139

Many mouse genes are “tissue-specific,” that is, they are present throughout the body but are expressed in only one of the animal’s many tissue types. (Other mouse genes are expressed throughout the body, or in multiple tissues.) Geneticists can study the regulation of a mouse gene by fusing the gene’s promoter region to the LacZ coding sequence and injecting the construct to create a transgenic mouse. Fusion of the mouse amylase promoter to LacZ yielded a Pamylase-LacZ construct.
Mice heterozygous for the resulting Pamylase-LacZ transgene displayed the LacZ expression exclusively in the pancreas. Would you expect homozygotes for the transgene to also display LacZ expression in the pancreas?.

#Unit 13. Methods in Biology

Mice homozygous for the transgene to display LacZ expression in the pancreas differ from the heterozygous mouse does, homozygote is a result of a cross between two heterozygous mice of the opposite transgenic line.
Mice homozygous for the transgene to display LacZ expression in the pancreas is unlikely to the heterozygous mouse does, homozygote is a result of a cross between two homozygous mice of the same transgenic line.
Mice homozygous for the transgene to display LacZ expression in the pancreas as the heterozygous mouse does, homozygote is a result of a cross between two homozygous mice of the different transgenic line.
Mice homozygous for the transgene to display LacZ expression in the pancreas as the heterozygous mouse does, homozygote is a result of a cross between two heterozygous mice of the same transgenic line.