Practice Questions

  1. Home
  2. Free Resources
  3. Practice Questions
  4. 2860
TLS Online TPP Program

#Question id: 2885

Which of the following function of DNA methylation in mammalian cell is incorrect?

#Unit 2. Cellular Organization

  1. The principal general function of DNA methylation in mammalian cells is to stabilize, or lock in, patterns of transcriptional silencing so that transcription is suppressed in highly methylated regions of chromatin.

  2. One of these is the regulation of gene expression, and it is the extent of DNA methylation in the key trans-acting regulatory elements that distinguishes actively transcribing genes from silenced genes.

  3. Highly repetitive DNA sequences, such as satellite repeats in pericentromeric heterochromatin and dispersed transposons, are extensively methylated, but there is also significant—though more sporadic—methylation in the main body (exons and introns) of genes and in intergenic regions.

  4. Patterns of gene expression that defines the identity of cells or that allow just one of the two alleles to be normally expressed can be locked in by DNA methylation.

More Questions
TLS Online TPP Program

#Question id: 19744

#Unit 3. Fundamental Processes

Which of the following statement is incorrect regarding Cdc 13
TLS Online TPP Program

#Question id: 19745

#Unit 3. Fundamental Processes

Shelterin is the complex of six protein (TRF1, TRF2, Rap1, TIN2, TPP1, and POT1), below some of the statements are given regarding POT1, choose the correct statement 
a) POT1 binding to single-stranded telomere DNA and promote telomere activity.
b) POT1 binding to single-stranded telomere DNA inhibits telomere activity.
c) POT1 acts as antagonist of Cdc13 which inhibits the telomere activity.
d) POT1 helps in recruitment of telomerase 
TLS Online TPP Program

#Question id: 19746

#Unit 3. Fundamental Processes

Cells that lack POT1 protein show dramatically 
TLS Online TPP Program

#Question id: 19747

#Unit 3. Fundamental Processes

Which proteins bound at the telomere to distinguish telomeres from other DNA ends in the cell prevents telomeres from normal DSBR
TLS Online TPP Program

#Question id: 19748

#Unit 3. Fundamental Processes

Circularisation of telomere known as
TLS Online TPP Program

#Question id: 19749

#Unit 3. Fundamental Processes

Telomeres form a looped structure in the cell called as t-loop and it is accomplished by