TLS Online TPP Program

#Question id: 408


Which of the following compounds has the largest negative value for the standard free-energy change (DG'°) upon hydrolysis?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. Acetic anhydride

  2. Glucose 6-phosphate

  3. Glutamine

  4. Glycerol 3-phosphate

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TLS Online TPP Program

#Question id: 12182

#Unit 2. Cellular Organization

The cell cycle is controlled by protein kinases that comprise a catalytic subunit and a regulatory subunit. Which of the following statement is correct regarding to these subunits?

TLS Online TPP Program

#Question id: 12183

#Unit 2. Cellular Organization

Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?

TLS Online TPP Program

#Question id: 12183

#Unit 1. Molecules and their Interaction Relevant to Biology

Following statements are regarding to regulation of S phase and mitotic cyclin levels in budding yeast.
A. In late anaphase, the anaphase-promoting complex (APC/C) ubiquitinylates S phase and mitotic cyclins.
B. In late anaphase, the anaphase-promoting complex (APC/C) phosphorylates S phase and mitotic cyclins.
C. During exit from mitosis and G1, Cdh1 is dephosphorylated and active; during S phase and mitosis, Cdh1 is phosphorylated and dissociates from APC/C, and APC/C becomes inactive.
D. During exit from mitosis and G1, Cdh1 is phosphorylated and active; during S phase and mitosis, Cdh1 is dephosphorylated and dissociates from APC/C, and APC/C becomes inactive.
E. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, phosphorylate Cdh1 at the G1–S phase transition.
F. The G1/S phase CDKs, which themselves are not APC/CCdh1 substrates, ubiquitinylates Cdh1 at the G1–S phase transition.
Which of the following combination is correct?

TLS Online TPP Program

#Question id: 12184

#Unit 2. Cellular Organization

Following graph represent Control of S phase onset in S. cerevisiae by regulated proteolysis of the S phase inhibitor Sic1. 
Which of the following is correct according to graph?

TLS Online TPP Program

#Question id: 12184

#Unit 1. Molecules and their Interaction Relevant to Biology

Following graph represent Control of S phase onset in S. cerevisiae by regulated proteolysis of the S phase inhibitor Sic1. 
Which of the following is correct according to graph?

TLS Online TPP Program

#Question id: 12185

#Unit 2. Cellular Organization

Mitotic CDKs affect nuclear envelope components by specific mechanism. Which of the following statement is not related to this mechanism?