Which of the following is a correct prediction about processing and secretion of Hedgehog protein ?

a) the freed N-terminal is not involved in signaling and is often degraded

b) the freed C-terminal is not involved in signaling and is often degraded

c) the N-terminal becomes the active Hedgehog protein intended for secretion

d) the C-terminal becomes the active Hedgehog protein intended for secretion

#Question id: 3823

#Unit 3. Fundamental Processes

Regarding DNA replication and DNA synthesis, which, if any, of the following statements is incorrect?

#Question id: 3824

#Unit 3. Fundamental Processes

State whether the following statements is true/false regarding DNA replication.

1. The polymerization of DNA is essentially irreversible due to the hydrolysis of pyrophosphate.

2. On average about twenty errors are made during each replication of the human genome.

3. DNA polymerase I possesses 5ʹ → 3ʹ exonuclease activity.

4. All DNA ligase enzymes use ATP as a cosubstrate.

5. The purpose of SSB is to prevent single-stranded DNA from folding back on itself to form double-helical regions.

#Question id: 3825

#Unit 3. Fundamental Processes

Telomeres are the repetitive sequence of T's and G's that are present in the eukaryotes to protect the random cleavage from nucleases. These telomeres are synthesized by the enzyme telomerase. Which of the following are the properties of enzyme telomerase?

#Question id: 3826

#Unit 3. Fundamental Processes

Which scientists first gave experimental evidence that DNA is the genetic material?

#Question id: 3827

#Unit 3. Fundamental Processes

It takes about the same amount of time for eukaryotic chromosomes to be replicated in vivo as it does for E. coli. Why is this true?

#Question id: 3828

#Unit 3. Fundamental Processes

Why does E. coli need both DNA polymerase III and DNA polymerase I?