In neurons, the concentration of K⁺ is much higher inside than outside the cell, while the reverse is the case for Na⁺. This concentration difference  is established by:

#Question id: 1241

#Unit 4. Cell Communication and Cell Signaling

Which of the following is a common step in the opening/closing of ion channels by acetylcholine and rhodopsin binding to their receptors?

#Question id: 1242

#Unit 4. Cell Communication and Cell Signaling

Rhodopsin, a light-sensitive GPCR whose role in vision is dependent on its phosphorylation status, is influenced in part by the protein arrestin.  Which of the following is TRUE with regard to rhodopsin and vision?

#Question id: 1243

#Unit 4. Cell Communication and Cell Signaling

One form of receptor desensitization can be mediated by negative feedback involving phosphorylation of the receptor itself by a kinase activated downstream of a second messenger. The phosphorylated receptor likely:

#Question id: 1244

#Unit 4. Cell Communication and Cell Signaling

Which type of experimental evidence shows that the intrinsic GTPase activity of the Gα subunit is important for terminating effector activation?

#Question id: 1245

#Unit 4. Cell Communication and Cell Signaling

Many PTB-containing proteins act as docking sites for multiple proteins. If these proteins are involved in the RTK signal transduction pathway, they most likely:

#Question id: 1246

#Unit 4. Cell Communication and Cell Signaling

An SH2-containing protein contains a mutation that changes its binding pocket such that tyrosine and phosphotyrosine bind with equal affinity. As a result, MEK activity: