TLS Online TPP Program

#Question id: 14402


Baby hamster kidney cells are immobilised in alginate beads. The average particle diameter is 5 mm. Rate of oxygen consumption at a bulk concentration of 8 x 10 ^-3 kg 0 2 m ^-3 is 8.4 x 10 ^-5 kg s^- 1 m^-3 catalyst. The effective diffusivity of oxygen in the beads is 1.88 x 10^ -9 m 2 s^- 1. Assume that the oxygen concentration at the surface of the catalyst is equal to the bulk concentration, and that oxygen uptake follows zero-order kinetics. calculate the observable Thiele modulus. 

#Section 5: Bioprocess Engineering and Process Biotechnology
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