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TLS Online TPP Program

#Question id: 3274

The common edible frog of Europe is a hybrid between two species, Rana lessonae and Rana ridibunda. The hybrids were first described in 1758 and have a wide distribution, from France across central Europe to Russia. Both male and female hybrids exist, but when they mate among themselves, they are rarely successful in producing offspring. What can you infer from this information?

#Section 3: Genetics, Cellular and Molecular Biology

  1. Postzygotic isolation exists between the two frog species.

  2. Prezygotic isolation exists between the two frog species.

  3. These two species are likely in the process of fusing back into one species.

  4. The hybrids form a separate species under the biological species concept.

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TLS Online TPP Program

#Question id: 14134

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

PAM stands for ___
TLS Online TPP Program

#Question id: 14135

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is correct about PAM matrix? 
TLS Online TPP Program

#Question id: 14136

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about global alignment? 
(A) Global alignment is based on the Needleman–Wunsch algorithm.
(B) In Global alignment algorithm, an optimal alignment is obtained over the entire lengths of the two sequences.
(C) It is only suitable for aligning two closely related sequences that are of the same length.
(D) GAP is a web-based pairwise global alignment program.
TLS Online TPP Program

#Question id: 14137

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Consider the following alignment of two DNA sequences:
                            AGTAAC
                            AA_ _AC

Assuming an affine gap scoring scheme of an identity matrix for substitution, a gap initiation penalty of 1 and a gap extension penalty of 0.1, the score of the alignment is _________
TLS Online TPP Program

#Question id: 14138

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

BLAST uses heuristics to align a query sequence with all sequences in a database. 
Reason(R): BLASTX uses protein sequences as queries to search against a protein sequence database.
TLS Online TPP Program

#Question id: 14139

#Section 7: Recombinant DNA technology and Other Tools in Biotechnology

Which of the following statement is incorrect about sequence similarity and sequence identity?