Continuous cell lines are the cell lines that has gained the ability for infinite growth after transformation, which can occur spontaneously or can be chemically or virally induced. 

TLS Online TPP Program

#Id: 8195

#Unit 2. Cellular Organization

A Pex 2, Pex 10, and Pex 12 complex embedded in the peroxisomal membrane transfers Ubiquitin to two embedded Pex 5 receptors.

TLS Online TPP Program

#Id: 8196

#Unit 2. Cellular Organization

The AAA ATPases Pex1 and Pex6 complex use the energy from ATP hydrolysis and causing the detachment of Pex 5 receptors into cytosol.

TLS Online TPP Program

#Id: 8197

#Unit 2. Cellular Organization

Zellweger syndrome

Autosomal recessive Mutations in any of a dozen different peroxins, the most common being Pex1, cause an impairment in peroxisomal protein import.

TLS Online TPP Program

#Id: 8198

#Unit 2. Cellular Organization

Lysosomes are membrane-enclosed organelles filled with soluble hydrolytic enzymes that digest macromolecules.

TLS Online TPP Program

#Id: 8199

#Unit 2. Cellular Organization

Lysosomes contain about 40 types of hydrolytic enzymes, All are acid hydrolases, work best at acidic pH including: proteases, nucleases, glycosidases, lipases, phospholipases, phosphatases, and sulfatases.

TLS Online TPP Program

#Id: 8200

#Unit 2. Cellular Organization

For optimal activity, of acid hydrolases they need to be: Activated by proteolytic cleavage Requires an acid environment.