TLS Online TPP Program

#Question id: 15849


Host-pathogen interactions are an ongoing arms race; pathogens evolve to express unique structures that avoid host detection, and the host germline-encoded recognition system co-evolves to match these new challenges. However, because pathogens generally have much shorter life cycles than their vertebrate hosts, and some utilize error-prone DNA polymerases to replicate their genomes, pathogens can evolve rapidly to evade host encoded recognition systems. Which error prone DNA polymerase is used  by human?

#Unit 4. Cell Communication and Cell Signaling
  1. DNA Polymerase α
  2. DNA Polymerase β
  3. DNA Polymerase µ
  4. DNA Polymerase ɳ
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TLS Online TPP Program

#Question id: 28688

#Unit 2. Cellular Organization

Ca2+ is released into the cytosol from the ER lumen through the operation of____

TLS Online TPP Program

#Question id: 28689

#Unit 2. Cellular Organization

 A special type of endoplasmic reticulum of muscle cells that involved in increasing the cytosolic Ca2+ concentration for skeletal muscle contraction ? 

TLS Online TPP Program

#Question id: 28690

#Unit 2. Cellular Organization

A pathway of protein trafficking that flows through the ER is called____

TLS Online TPP Program

#Question id: 28691

#Unit 2. Cellular Organization

ER targeting sequence___

TLS Online TPP Program

#Question id: 28692

#Unit 2. Cellular Organization

Which one of the following statements about signal recognition particles (SRPs) is correct?
a) It is a cytosolic ribonucleoprotein
b) It docks with a receptor on the surface of the ER membrane.
c) It is an integral membrane protein
d) It transiently binds to both the ER signal sequence at the C-terminus and the large (60S) ribosomal subunit
e) It acts as a scaffold for the hexamer

TLS Online TPP Program

#Question id: 28693

#Unit 2. Cellular Organization

There are some given statements about co-translational translocation in endoplasmic reticulum

a)SRP and the nascent polypeptide chain–ribosome complex bind to the integral membrane translocon

b)SRP and the nascent polypeptide chain–ribosome complex is strengthened by the binding of GTP to both the SRP and its receptor.

c)ER signal sequence emerges from the ribosome, it is bound by a signal recognition particle (SRP)

d)Hydrolysis of the bound GTP accompanies disassembly of the SRP and SRP receptor

e)Hydrolysis of the bound GTP initiates opening of the translocon, where translocation can take place


Which of the following statement is incorrect?