Host-pathogen interactions are an ongoing arms race; pathogens evolve to express unique structures that avoid host detection, and the host germline-encoded recognition system co-evolves to match these new challenges. However, because pathogens generally have much shorter life cycles than their vertebrate hosts, and some utilize error-prone DNA polymerases to replicate their genomes, pathogens can evolve rapidly to evade host encoded recognition systems. Which error prone DNA polymerase is used  by human?

TLS Online TPP Program

#Question id: 33908

#Unit 2. Cellular Organization

How is the linking number altered if one DNA strand is broken

TLS Online TPP Program

#Question id: 33909

#Unit 2. Cellular Organization

What is the Lk of a 5,000 bp circular duplex DNA molecule with a nick in one strand?

TLS Online TPP Program

#Question id: 33910

#Unit 2. Cellular Organization

What is the Lk of a 5,000 bp circular duplex DNA molecule after eight enzymatic turnovers by a single molecule of DNA gyrase in the presence of ATP?

TLS Online TPP Program

#Question id: 33911

#Unit 2. Cellular Organization

What is the Lk of a 5,000 bp circular duplex DNA molecule after eight enzymatic turnovers by a single molecule of DNA gyrase in the presence of ATP followed by 8 enzymatic turnovers by a single molecule of bacterial type I topoisomerase

TLS Online TPP Program

#Question id: 33912

#Unit 2. Cellular Organization

A. When a DNA molecule is negatively supercoiled, it is underwound. 

B. Any structural change involving DNA strand separation becomes more likely in negatively supercoiled DNA. 

C. Negative supercoiling makes establishment of left-handed Z-DNA in a segment of DNA 

D. The formation of plectonemic or solenoidal supercoils is favored as a means of negative supercoiling.

Find true and false

TLS Online TPP Program

#Question id: 33913

#Unit 2. Cellular Organization

A. Underwinding of a B-DNA helix might facilitate or stabilize the formation of Z-DNA.

B. Underwinding aids in the transition by providing a local region of unwound DNA that allows the shift to Z-DNA.

C. Overwinding of a B-DNA helix might facilitate or stabilize the formation of Z-DNA.

D. Overwinding aids in the transition by providing a local region of unwound DNA that allows the shift to Z-DNA.

What is correct combination of statements