TLS Online TPP Program

#Question id: 1596


Which one of the following is function of Class III MHC genes?

#Unit 4. Cell Communication and Cell Signaling
  1. predominantly on APCs (macrophages, dendritic cells, and B cells), where they primarily present exogenous antigenic

  2. glycoproteins expressed on the surface of nearly all nucleated cells

  3. presentation of endogenous peptide antigens to CD8+ T cells.

  4. immune functions, including components of the complement system and molecules involved in inflammation.

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TLS Online TPP Program

#Question id: 15841

#Unit 8. Inheritance Biology

In the yeast cross of ade2 met14 his3 x + + +, a total of 120 tetrads are analyzed. The following tetrad types are found in the numbers shown below each tetrad. The markers ade2, met14, and his3 are abbreviated a, m, and h and the wild type allele of each gene is indicated by +.
 
Based on your numbers, calculate the distance between his2 and his4.

TLS Online TPP Program

#Question id: 15842

#Unit 8. Inheritance Biology

In the yeast cross of ade2 met14 his3 x + + +, a total of 120 tetrads are analyzed. The markers ade2, met14, and his3 are abbreviated a, m, and h and the wild type allele of each gene is indicated by +.
      
Given three locus from above, which locus shows the tetratype (T)

TLS Online TPP Program

#Question id: 15843

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml.           What is the distance between the ts-1 and ts-2 mutations in m.u.?

TLS Online TPP Program

#Question id: 15844

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml.  
If the total size of the phage is 5 x 104 bp and the total genetic map length of the phage is 100 m.u., about how far apart are the mutations in base pairs?

TLS Online TPP Program

#Question id: 15845

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. Find out the relative order of sm, ts-1 and ts-2?

TLS Online TPP Program

#Question id: 15846

#Unit 8. Inheritance Biology

You have isolated two temperature-sensitive mutations in phage l that you suspect may be in the same gene. These phage mutants are called ts-1 and ts-2. Each mutant will form plaques at 35˚C but not at 42˚C. You cross ts-1 to ts-2 phage by coinfecting E. coli at the permissive temperature of 35˚C. When the resulting phage lysate is plated at 35˚C you count 10,000 plaques per ml of phage lysate, but when the same phage lysate is plated at 42˚C, there are only 80 plaques per ml. the relative order is sm→ts-2→ts-1, find out the distances you can calculate in m.u.?