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                                TLS Online TPP Program
                                                    #Question id: 33907
#Unit 2. Cellular Organization
A circular DNA molecule with 580,070 bp. Calculate the molecular weight and contour length (when relaxed) of this molecule. What is Lko for the Mycoplasma chromosome? If σ=-  0.06, what is Lk?
 
                                                    TLS Online TPP Program
                                                    #Question id: 33908
#Unit 2. Cellular Organization
How is the linking number altered if one DNA strand is broken
 
                                                    TLS Online TPP Program
                                                    #Question id: 33909
#Unit 2. Cellular Organization
What is the Lk of a 5,000 bp circular duplex DNA molecule with a nick in one strand?
 
                                                    TLS Online TPP Program
                                                    #Question id: 33910
#Unit 2. Cellular Organization
What is the Lk of a 5,000 bp circular duplex DNA molecule after eight enzymatic turnovers by a single molecule of DNA gyrase in the presence of ATP?
 
                                                    TLS Online TPP Program
                                                    #Question id: 33911
#Unit 2. Cellular Organization
What is the Lk of a 5,000 bp circular duplex DNA molecule after eight enzymatic turnovers by a single molecule of DNA gyrase in the presence of ATP followed by 8 enzymatic turnovers by a single molecule of bacterial type I topoisomerase
 
                                                    TLS Online TPP Program
                                                    #Question id: 33912
#Unit 2. Cellular Organization
A. When a DNA molecule is negatively supercoiled, it is underwound. 
B. Any structural change involving DNA strand separation becomes more likely in negatively supercoiled DNA. 
C. Negative supercoiling makes establishment of left-handed Z-DNA in a segment of DNA 
D. The formation of plectonemic or solenoidal supercoils is favored as a means of negative supercoiling.
Find true and false
 
                                                    